D-arabinose 1-dehydrogenase (NAD(P)+)
In enzymology, a D-arabinose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.117) is an enzyme that catalyzes the chemical reaction
- D-arabinose + NAD(P)+ D-arabinono-1,4-lactone + NAD(P)H + H+
| D-arabinose 1-dehydrogenase [NAD(P)+] | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.117 | ||||||||
| CAS number | 37250-48-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The 3 substrates of this enzyme are D-arabinose, NAD+, and NADP+, whereas its 4 products are D-arabinono-1,4-lactone, NADH, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-arabinose:NAD(P)+ 1-oxidoreductase. This enzyme is also called D-arabinose 1-dehydrogenase [NAD(P)+].
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2H6E.
gollark: Also, they now make GPUs and optical networking gear and WiFi chips and a bunch of other random nonsense.
gollark: You DO realize that they are massively bigger than AMD and make up basically the entire server market still?
gollark: What? No.
gollark: IIRC their Atoms from the time were pretty competitive with ARM. But they never took off because... I'm not actually sure.
gollark: They did, they just didn't seem to do it very effectively.
References
- Cline AL, Hu AS (1965). "The isolation of three sugar dehydrogenases from a psuedomonad [sic]". J. Biol. Chem. 240 (11): 4488–92. PMID 5845847.
- Cline AL, Hu AS (1965). "Enzymatic characterization and comparison of three sugar dehydrogenases from a pseudomonad". J. Biol. Chem. 240 (11): 4493–7. PMID 5845848.
- Cline AL, Hu AS (1965). "Some physical properties of three sugar dehydrogenases from a pseudomonad". J. Biol. Chem. 240 (11): 4498–502. PMID 5845849.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.