CM156

CM156[1] is a piperazine based chemical compound with nanomolar affinity for both sigma receptor subtypes that has been shown to counteract the deleterious effects of administered cocaine.

CM156

Identifiers
IUPAC name 3-[4-(4-cyclohexylpiperazin-1-yl)butyl]-1,3-benzothiazole-2-thione
PubChem CID	17756659
ChemSpider	23325411
Chemical and physical data
Formula	C21H31N3S2
Molar mass	389.62 g·mol^−1
3D model (JSmol)	Interactive image
SMILES c1ccc2c(c1)n(c(=S)s2)CCCCN3CCN(CC3)C4CCCCC4
InChI InChI=1S/C21H31N3S2/c25-21-24(19-10-4-5-11-20(19)26-21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h4-5,10-11,18H,1-3,6-9,12-17H2 Key:FJGOTAJCEJCFEV-UHFFFAOYSA-N

See also

• 3C-PEP

References

1. Xu YT, Kaushal N, Shaikh J, Wilson LL, Mésangeau C, McCurdy CR, Matsumoto RR (May 2010). "A novel substituted piperazine, CM156, attenuates the stimulant and toxic effects of cocaine in mice". The Journal of Pharmacology and Experimental Therapeutics. 333 (2): 491–500. doi:10.1124/jpet.109.161398. PMC 2872963. PMID 20100904.