Benzophenone synthase
In enzymology, a benzophenone synthase (EC 2.3.1.151) is an enzyme that catalyzes the chemical reaction
- 3 malonyl-CoA + 3-hydroxybenzoyl-CoA 4 CoA + 2,3',4,6-tetrahydroxybenzophenone + 3 CO2
| benzophenone synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.1.151 | ||||||||
| CAS number | 175780-21-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are malonyl-CoA and 3-hydroxybenzoyl-CoA, whereas its 3 products are CoA, 2,3',4,6-tetrahydroxybenzophenone, and CO2.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:3-hydroxybenzoyl-CoA malonyltransferase.
References
- Beerhues L (April 1996). "Benzophenone synthase from cultured cells of Centaurium erythraea". FEBS Letters. 383 (3): 264–6. doi:10.1016/0014-5793(96)00265-7. PMID 8925910.
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