Apiose 1-reductase
In enzymology, an apiose 1-reductase (EC 1.1.1.114) is an enzyme that catalyzes the chemical reaction
- D-apiitol + NAD+ D-apiose + NADH + H+
| apiose 1-reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.114 | ||||||||
| CAS number | 37250-45-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are D-apiitol and NAD+, whereas its 3 products are D-apiose, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-apiitol:NAD+ 1-oxidoreductase. Other names in common use include D-apiose reductase, and D-apiitol reductase.
References
- Hanna R, Picken M, Mendicino J (1973). "Purification of a specific D-apiitol dehydrogenase from a Micrococcus isolated from the surface of germinating parsley seeds". Biochim. Biophys. Acta. 315: 259–271. doi:10.1016/0005-2744(73)90255-6.
- Neal DL, Kindel PK (1970). "D-apiose reductase from Aerobacter aerogenes". J. Bacteriol. 101 (3): 910–5. PMC 250409. PMID 4314545.
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