Anthranilate 3-monooxygenase (FAD)

Anthranilate 3-monooxygenase (FAD) (EC 1.14.14.8, anthranilate 3-hydroxylase, anthranilate hydroxylase) is an enzyme with systematic name anthranilate,FAD:oxygen oxidoreductase (3-hydroxylating).[1] This enzyme catalyses the following chemical reaction

anthranilate + FADH2 + O2 3-hydroxyanthranilate + FAD + H2O
Anthranilate 3-monooxygenase (FAD)
Identifiers
EC number1.14.14.8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

The enzyme from the bacterium Geobacillus thermodenitrificans participates in tryptophan degradation.

References

  1. Liu X, Dong Y, Li X, Ren Y, Li Y, Wang W, Wang L, Feng L (February 2010). "Characterization of the anthranilate degradation pathway in Geobacillus thermodenitrificans NG80-2". Microbiology. 156 (Pt 2): 589–95. doi:10.1099/mic.0.031880-0. PMID 19942660.
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