Anthocyanidin reductase
In enzymology, an anthocyanidin reductase (EC 1.3.1.77) is an enzyme that catalyzes the chemical reaction
- a flavan-3-ol + 2 NAD(P)+ an anthocyanidin + 2 NAD(P)H + H+
| Anthocyanidin reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.3.1.77 | ||||||||
| CAS number | 93389-48-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The 3 substrates of this enzyme are flavan-3-ol, NAD+, and NADP+, whereas its 4 products are anthocyanidin, NADH, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is flavan-3-ol:NAD(P)+ oxidoreductase. Other names in common use include AtANR, and MtANR. This enzyme participates in flavonoid biosynthesis.
References
- Xie DY, Sharma SB, Paiva NL, Ferreira D, Dixon RA (2003). "Role of anthocyanidin reductase, encoded by BANYULS in plant flavonoid biosynthesis". Science. 299 (5605): 396–399. doi:10.1126/science.1078540. PMID 12532018.
- Xie DY, Sharma SB, Dixon RA (2004). "Anthocyanidin reductases from Medicago truncatula and Arabidopsis thaliana". Arch. Biochem. Biophys. 422 (1): 91–102. doi:10.1016/j.abb.2003.12.011. PMID 14725861.
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