(+)-trans-carveol dehydrogenase
In enzymology, a (+)-trans-carveol dehydrogenase (EC 1.1.1.275) is an enzyme that catalyzes the chemical reaction
- (+)-trans-carveol + NAD+ (+)-(S)-carvone + NADH + H+
| Identifiers | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| EC number | 1.1.1.275 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are (+)-trans-carveol and NAD+, whereas its 3 products are (+)-(S)-carvone, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (+)-trans-carveol:NAD+ oxidoreductase. This enzyme is also called carveol dehydrogenase. This enzyme participates in monoterpenoid biosynthesis and the degradation of the terpenes limonene and pinene.
References
- Bouwmeester HJ, Gershenzon J, Konings MC, Croteau R (1998). "Biosynthesis of the Monoterpenes Limonene and Carvone in the Fruit of Caraway : I. Demonstration of Enzyme Activities and Their Changes with Development". Plant Physiol. 117 (3): 901–12. doi:10.1104/pp.117.3.901. PMC 34944. PMID 9662532.
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