Urodynamic testing

Urodynamic testing or urodynamics is a study that assesses how the bladder and urethra are performing their job of storing and releasing urine. Urodynamic tests can help explain symptoms such as:

  • incontinence[1]
  • frequent urination
  • sudden, strong urges to urinate but nothing comes out
  • problems starting a urine stream
  • painful urination
  • problems emptying the bladder completely
  • recurrent urinary tract infections
Urodynamic testing
Urinary bladder
Purposestoring and releasing urine analysis

Urodynamic tests are usually performed in Urology, Gynecology, OB/GYN, Internal medicine, and Primary care offices. Urodynamics will provide the physician with the information necessary to diagnose the cause and nature of a patient's incontinence, thus giving the best treatment options available. Urodynamics is typically conducted by urologists or urogynecologists.

Purpose of testing

The tests are most often arranged for men with enlarged prostate glands, and for women with incontinence that has either failed conservative treatment or requires surgery. Probably the most important group in whom these tests are performed are those with a neuropathy such as spinal injury. In some of these patients (dependent on the level of the lesion), the micturition reflex can be essentially out of control and the detrusor pressures generated can be life-threatening.

Symptoms reported by the patient are an unreliable guide to the underlying dysfunction of the lower urinary tract. The purpose of urodynamics is to provide objective confirmation of the pathology that a patient's symptoms would suggest.[2]

For example, a patient complaining of urinary urgency (or rushing to the toilet), with increased frequency of urination can have overactive bladder syndrome. The cause of this might be detrusor overactivity, in which the bladder muscle (the detrusor) contracts unexpectedly during bladder filling. Urodynamics can be used to confirm the presence of detrusor overactivity, which may help guide treatment. An overactive detrusor can be associated with urge incontinence. The American Urogynecologic Society does not recommend that urodynamics are part of initial diagnosis for uncomplicated overactive bladder.[3]

Specific tests

These tests may be as simple as urinating behind a curtain while a doctor listens, but are usually more extensive in western medicine. A typical urodynamic test takes about 30 minutes to perform. It involves the use of a small catheter used to fill the bladder and record measurements.[4] What is done depends on what the presenting problem is, but some of the common tests conducted are;

  • Post-void residual volume: Most tests begin with the insertion of a urinary catheter/transducer following complete bladder emptying by the patient. The urine volume is measured (this shows how efficiently the bladder empties). High volumes (180 ml) may be associated with urinary tract infections.[5] A volume of greater than 50 ml in children has been described as constituting post-void residual urine.[6] High levels can be associated with overflow incontinence.
  • The urine is often sent for microscopy and culture to check for infection.
  • Uroflowmetry: Free uroflowmetry measures how fast the patient can empty his/her bladder. Pressure uroflowmetry again measures the rate of voiding, but with simultaneous assessment of bladder and rectal pressures. It helps demonstrate the reasons for difficulty in voiding, for example bladder muscle weakness or obstruction of the bladder outflow.
  • Multichannel cystometry: measures the pressure in the rectum and in the bladder, using two pressure catheters, to deduce the presence of contractions of the bladder wall, during bladder filling, or during other provocative maneuvers. The strength of the urethra can also be tested during this phase, using a cough or Valsalva maneuver, to confirm genuine stress incontinence.
  • Urethral pressure profilometry: measures strength of sphincter contraction.[7]
  • Electromyography (EMG) measurement of electrical activity in the bladder neck.
  • Assessing the "tightness" along the length of the urethra.
  • Fluoroscopy (moving video x-rays) of the bladder and bladder neck during voiding.

Standardization

Males with benign prostate hyperplasia are influenced by voiding position: in the sitting position, the PVR, Qmax and TQ were shown to improve.[8] Apart from the possibilities in the management of this condition, it shows that measurements of urodynamics should be performed in a standardized position, else false-positive or negative findings may be found.

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References
  1. van Leijsen SA, Kluivers KB, Mol BW, et al. (2009). "Protocol for the value of urodynamics prior to stress incontinence surgery (VUSIS) study: a multicenter randomized controlled trial to assess the cost effectiveness of urodynamics in women with symptoms of stress urinary incontinence in whom surgical treatment is considered". BMC Women's Health. 9: 22. doi:10.1186/1472-6874-9-22. PMC 2722584. PMID 19622153.
  2. Rosier P (2019). "Contemporary diagnosis of lower urinary tract dysfunction". F1000Res. 8: 644. doi:10.12688/f1000research.16120.1. PMC 6509958. PMID 31119030.
  3. American Urogynecologic Society (May 5, 2015), "Five Things Physicians and Patients Should Question", Choosing Wisely: an initiative of the ABIM Foundation, American Urogynecologic Society, retrieved June 1, 2015, which cites: *Gormley, EA; Lightner, DJ; Faraday, M; Vasavada, SP (May 2015). "Diagnosis and Treatment of Overactive Bladder (Non-Neurogenic) in Adults: AUA/SUFU Guideline Amendment". The Journal of Urology. 193 (5): 1572–80. doi:10.1016/j.juro.2015.01.087. PMID 25623739.
  4. Rosier Pfwm Schaefer W, Lose G, Goldman HB, Guralnick M, Eustice S, Dickinson T, Hashim H (2017). "International Continence Society Good Urodynamic Practices and Terms 2016: Urodynamics, uroflowmetry, cystometry, and pressure-flow study". Neurourol Urodyn. 36 (5): 1243–1260. doi:10.1002/nau.23124. PMID 27917521.CS1 maint: multiple names: authors list (link)
  5. Truzzi JC, Almeida FM, Nunes EC, Sadi MV (July 2008). "Residual urinary volume and urinary tract infection--when are they linked?". J. Urol. 180 (1): 182–5. doi:10.1016/j.juro.2008.03.044. PMID 18499191.
  6. Chang SJ, Yang SS (October 2009). "Variability, related factors and normal reference value of post-void residual urine in healthy kindergarteners". J. Urol. 182 (4 Suppl): 1933–8. doi:10.1016/j.juro.2009.02.086. PMID 19695621.
  7. "loyola Univ. Health Sys. - Urology - Health Topics/Urodynamic Testing".
  8. de Jong, Y; Pinckaers, JH; Ten Brinck, RM; Lycklama À Nijeholt, AA; Dekkers, OM (2014). "Urinating Standing versus Sitting: Position Is of Influence in Men with Prostate Enlargement. A Systematic Review and Meta-Analysis". PLOS ONE. 9 (7): e101320. doi:10.1371/journal.pone.0101320. PMC 4106761. PMID 25051345.

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