Molecular probe

A molecular probe is a group of atoms or molecules used in molecular biology or chemistry to study the properties of other molecules or structures. If some measurable property of the molecular probe used changes when it interacts with the analyte (such as a change in absorbance), the interactions between the probe and the analyte can be studied. This makes it possible to indirectly study the properties of compounds and structures which may be hard to study directly. The choice of molecular probe will depend on which compound or structure is being studied as well as on what property is of interest. Radioactive DNA or RNA sequences are used in molecular genetics to detect the presence of a complementary sequence by molecular hybridization.[1]

A compass of molecular probes

Common probes

gollark: Right, so don't shove people in very busy rooms for 5 hours a day.
gollark: If school was optimized for that, you wouldn't spend 5 hours a day not allowed to talk.
gollark: Well, you're:- legally required to be there- may actually be getting food from the same companies as prisons- are forced to move around between lessons arbitrarily when a bell occurs- aren't allowed to interact with friends and whatever much of the day- are forced to obey the staff and do whatever random work is set
gollark: That would be neat, or at least run in-person schools less like prisons.
gollark: > It's hard to compare certainty of one thing with a small risk of anotherThis can be done using "multiplication".

References

  1. "Cancerweb Molecular Probe Definition".
  2. Sirbu, D.; Zeng, L.; Waddell, P. G.; Benniston, A. C. (2019-08-07). "An unprecedented oxidised julolidine-BODIPY conjugate and its application in real-time ratiometric fluorescence sensing of sulfite". Organic & Biomolecular Chemistry. 17 (31): 7360–7368. doi:10.1039/C9OB01316D. ISSN 1477-0539.


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