List of conditions treated with hematopoietic stem cell transplantation
Hematopoietic stem cell transplantation may be used to treat a number of conditions both congenital and acquired.
Acquired
- Malignancies
- Hematological
- Leukemias
- Acute lymphoblastic leukemia (ALL)
- Acute myeloid leukemia (AML)
- Chronic lymphocytic leukemia (CLL)
- Chronic myelogenous leukemia (CML), accelerated phase or blast crisis
- Lymphomas
- Hodgkin's disease
- Non-Hodgkin's lymphoma
- Myelomas
- Multiple myeloma (Kahler's disease)
- Leukemias
- Solid tumor cancers
- Neuroblastoma
- Desmoplastic small round cell tumor
- Ewing's sarcoma
- Choriocarcinoma
- Hematological
- Hematologic disease
- Phagocyte disorders
- Anemias
- Paroxysmal nocturnal hemoglobinuria (PNH; severe aplasia)
- Aplastic anemia
- Acquired pure red cell aplasia
- Myeloproliferative disorders
- Polycythemia vera
- Essential thrombocytosis
- Myelofibrosis
- Metabolic disorders
- Amyloidoses
- Amyloid light chain (AL) amyloidosis
- Amyloidoses
- Environmentally-induced diseases
- Radiation poisoning
- Viral diseases
- Autoimmune diseases
Congenital
- Lysosomal storage disorders
- Lipidoses (disorders of lipid storage)
- Neuronal ceroid lipofuscinoses
- Infantile neuronal ceroid lipofuscinosis (INCL, Santavuori disease,)
- Jansky–Bielschowsky disease (late infantile neuronal ceroid lipofuscinosis)
- Sphingolipidoses
- Niemann–Pick disease
- Gaucher disease
- Leukodystrophies
- Adrenoleukodystrophy
- Metachromatic leukodystrophy
- Krabbe disease (globoid cell leukodystrophy)
- Neuronal ceroid lipofuscinoses
- Mucopolysaccharidoses
- Hurler syndrome (MPS I H, α-L-iduronidase deficiency)
- Scheie syndrome (MPS I S)
- Hurler–Scheie syndrome (MPS I H-S)
- Hunter syndrome (MPS II, iduronidase sulfate deficiency)
- Sanfilippo syndrome (MPS III)
- Morquio syndrome (MPS IV)
- Maroteaux–Lamy syndrome (MPS VI)
- Sly syndrome (MPS VII)
- Glycoproteinoses
- Mucolipidosis II (I-cell disease)
- Fucosidosis
- Aspartylglucosaminuria
- Alpha-mannosidosis
- Other
- Wolman disease (acid lipase deficiency)
- Lipidoses (disorders of lipid storage)
- Immunodeficiencies
- T-cell deficiencies
- Combined T- and B-cell deficiencies
- Severe combined immunodeficiency (SCID), all types
- Well-defined syndromes
- Phagocyte disorders
- Kostmann syndrome
- Shwachman–Diamond syndrome
- Immune dysregulation diseases
- Griscelli syndrome, type II
- Innate immune deficiencies
- NF-Kappa-B Essential Modulator (NEMO) deficiency (Inhibitor of Kappa Light Polypeptide Gene Enhancer in B Cells Gamma Kinase deficiency)
- Hematologic diseases
- Hemoglobinopathies
- Sickle cell disease
- β thalassemia major (Cooley's anemia)
- Anemias
- Cytopenias
- Hemophagocytic syndromes
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References
- Hütter G, Nowak D, Mossner M, Ganepola S, Müßig A, Allers K, Schneider T, Hofmann J, Kücherer C, Blau O, Blau IW, Hofmann WK, Thiel E (2009). "Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantation". N Engl J Med. 360 (7): 692–698. doi:10.1056/NEJMoa0802905. PMID 19213682.
- "Conditions stem cell transplant can cure". INDHEAL.
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