Isomethadol

Isomethadol is an opioid analgesic with a number of stereoisomers (viz. alpha and beta forms of dextro, laevo, and racemic isomers for a total of six) produced by the reduction of d,l-isomethadone with lithium aluminium hydride.[2] It was first produced in the United States in 1948. The salt used in research is the hydrochloride.

Isomethadol
Names
IUPAC name
6-(Dimethylamino)-5-methyl-4,4-diphenyl-3-hexanol
Identifiers
3D model (JSmol)
ChemSpider
UNII
Properties
C21H29NO
Molar mass 311.461
Melting point 125 to 126 °C (257 to 259 °F; 398 to 399 K)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

  1. May, Everette L.; Eddy, Nathan B. (1952). "The Isomethadols and their Acetyl Derivatives". The Journal of Organic Chemistry. 17 (9): 1210–1215. doi:10.1021/jo50009a005. ISSN 0022-3263.
  2. Merck Index, 11th edition, 5068


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