Hereditary hyperbilirubinemia

Hereditary hyperbilirubinemia refers to the condition where levels of bilirubin are elevated, for reasons that can be attributed to a metabolic disorder.

Hereditary hyperbilirubinemia
Bilirubin levels are increased by this condition
SpecialtyEndocrinology 

An example is Crigler–Najjar syndrome.

Symptoms

UGT1A1 gene mutations causes the condition. As a result, there can be reduced functionality of the bilirubin-UGT enzyme. Eventually it causes unconjugated hyperbilirubinemia and jaundice as substance accumulates in the body due to the reduced ability of the enzyme.[1]

Diagnosis

Management

gollark: Producing the hydrogen is incredibly loud, and in some versions breaks thermodynamics via energy efficiency upgrades, and otherwise uses several kRF/t of power.
gollark: Thanks to Mekanism I have *hydrogen-fuelled* jetpacks!
gollark: I have gregtech installed so it's actually "battery buffers".
gollark: Ah, ye olden IC2 batboxes.
gollark: A backpack filled with bats.

References

  1. Reference, Genetics Home. "Crigler-Najjar syndrome". Genetics Home Reference.

Further reading

Classification
External resources


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.