Lucey–Driscoll syndrome
Lucey–Driscoll syndrome is an autosomal recessive metabolic disorder affecting enzymes involved in bilirubin metabolism.[1] It is one of several disorders classified as a transient familial neonatal unconjugated hyperbilirubinemia.
| Lucey–Driscoll syndrome | |
|---|---|
| Other names | Transient familial neonatal hyperbilirubinemia |
 | |
| Lucey–Driscoll syndrome has an autosomal recessive pattern of inheritance. | |
| Specialty | DiseasesDB = 32677 |
Cause
The common cause is congenital, but it can also be caused by maternal steroids passed on through breast milk to the newborn. It is different from breast feeding-associated jaundice (breast-fed infants have higher bilirubin levels than formula-fed ones).
Genetics
A defect in the UGT1A1-gene, also linked to Crigler–Najjar syndrome and Gilbert's syndrome, is responsible for the congenital form of Lucey–Driscoll syndrome.
Diagnosis
Treatment
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gollark: *Somehow* there are something like twenty eBay listings for replacement screen assemblies but no repair instructions.
gollark: The screen backlight on my phone seems to have somehow ceased to exist suddenly. I can access it fine over adb and the touchscreen works, but the screen is entirely black regardless of configured brightness. Is this likely to be fixable at all?
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References
- "Lucey-Driscoll syndrome | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program". rarediseases.info.nih.gov. Retrieved 2017-08-27.
External links
| Classification | |
|---|---|
| External resources |
- Online Mendelian Inheritance in Man (OMIM): 237900 - transient familial neonatal hyperbilirubinemia, breast feeding jaundice included
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