Lucey–Driscoll syndrome
Lucey–Driscoll syndrome is an autosomal recessive metabolic disorder affecting enzymes involved in bilirubin metabolism.[1] It is one of several disorders classified as a transient familial neonatal unconjugated hyperbilirubinemia.
| Lucey–Driscoll syndrome | |
|---|---|
| Other names | Transient familial neonatal hyperbilirubinemia |
 | |
| Lucey–Driscoll syndrome has an autosomal recessive pattern of inheritance. | |
| Specialty | DiseasesDB = 32677 |
Cause
The common cause is congenital, but it can also be caused by maternal steroids passed on through breast milk to the newborn. It is different from breast feeding-associated jaundice (breast-fed infants have higher bilirubin levels than formula-fed ones).
Genetics
A defect in the UGT1A1-gene, also linked to Crigler–Najjar syndrome and Gilbert's syndrome, is responsible for the congenital form of Lucey–Driscoll syndrome.
Diagnosis
Treatment
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gollark: It does some random stuff and prints out debug info.
gollark: I made a LOØÞ:```04 b0 00 0804 10 01 ff04 e0 ff 0203 e0 a0 0004 de 03 0102 c0 a0 0002 dd a0 00ff 00 00 0004 aa 00 0107 ab 00 00```
gollark: Hmm, apparently my JLT instruction is not JLTing.
gollark: I dislike it.
References
- "Lucey-Driscoll syndrome | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program". rarediseases.info.nih.gov. Retrieved 2017-08-27.
External links
| Classification | |
|---|---|
| External resources |
- Online Mendelian Inheritance in Man (OMIM): 237900 - transient familial neonatal hyperbilirubinemia, breast feeding jaundice included
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