Cis-2-enoyl-CoA reductase (NADPH)
In enzymology, a cis-2-enoyl-CoA reductase (NADPH) (EC 1.3.1.37) is an enzyme that catalyzes the chemical reaction
- acyl-CoA + NADP+ cis-2,3-dehydroacyl-CoA + NADPH + H+
| cis-2-enoyl-CoA reductase (NADPH) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.3.1.37 | ||||||||
| CAS number | 72841-00-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are acyl-CoA and NADP+, whereas its 3 products are cis-2,3-dehydroacyl-CoA, NADPH, and H+.
Nomenclature
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is acyl-CoA:NADP+ cis-2-oxidoreductase. Other names in common use include NADPH-dependent cis-enoyl-CoA reductase, reductase, cis-2-enoyl coenzyme A, cis-2-enoyl-coenzyme A reductase, and cis-2-enoyl-CoA reductase (NADPH).
gollark: I mean, I'm a moderately okay programmer and sysadmin, but nobody pays me for it or anything.
gollark: 400Gbps Ethernet over fibre optic stuff is available now. Hilariously expensive of course.
gollark: It would be faster, probably, to use an internal NVMe disk or something as swap.
gollark: <@338036497087201291> You know you can do `math.random(0, 1)` if you want to pick 0 or 1 randomly?
gollark: It may not be a C++-knowledge thing as much as an understanding-and-dealing-with-algorithms-generally thing.
References
Further reading
- Mizugaki M, Nishimaki T, Shiraishi T, Kawaguchi A, Okuda S, Yamanaka H (November 1982). "Studies on the metabolism of unsaturated fatty acids. IX. Stereochemical studies of the reaction catalyzed by trans-2-enoyl-coenzyme A reductase of Escherichia coli". Journal of Biochemistry. 92 (5): 1649–54. PMID 6759504.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.