Alpha-santonin 1,2-reductase
In enzymology, an alpha-santonin 1,2-reductase (EC 1.3.1.47) is an enzyme that catalyzes the chemical reaction
- 1,2-dihydrosantonin + NAD(P)+ alpha-santonin + NAD(P)H + H+
| alpha-santonin 1,2-reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.3.1.47 | ||||||||
| CAS number | 111070-23-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The 3 substrates of this enzyme are 1,2-dihydrosantonin, NAD+, and NADP+, whereas its 4 products are alpha-santonin, NADH, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 1,2-dihydrosantonin:NAD(P)+ 1,2-oxidoreductase.
References
- Naik U, Mavuinkurve S (1987). "alpha-Santonin 1,2-reductase and its role in the formation of dihydrosantonin and lumisantonin by Pseudomonas cichorii S". Can. J. Microbiol. 33 (8): 658–62. doi:10.1139/m87-115. PMID 3690421.
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