Small nucleolar RNA snoMBI-87

Small nucleolar RNA MBI-87 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".[1]

Small nucleolar RNA SNORA36 family
Predicted secondary structure and sequence conservation of SNORA36
Identifiers
SymbolSNORA36
Alt. SymbolssnoMBI-87
RfamRF00340
Other data
RNA typeGene; snRNA; snoRNA; H/ACA-box
Domain(s)Eukaryota
GO0006396 0005730
SO0000594
PDB structuresPDBe

snoRNA MBI-87 was originally cloned from mouse brain tissues[2] and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure and has the conserved H/ACA-box motifs.

References

  1. Kiss T (April 2002). "Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions". Cell. 109 (2): 145–8. doi:10.1016/S0092-8674(02)00718-3. PMID 12007400.
  2. Hüttenhofer A, Kiefmann M, Meier-Ewert S, O'Brien J, Lehrach H, Bachellerie JP, Brosius J (June 2001). "RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse". The EMBO Journal. 20 (11): 2943–53. doi:10.1093/emboj/20.11.2943. PMC 125495. PMID 11387227.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.