Small nucleolar RNA SNORD30

Small nucleolar RNA SNORD30 (U30) is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U30 is encoded within the U22 snoRNA host gene (UHG) in mammals[1] and is thought to act as a 2'-O-ribose methylation guide for ribosomal RNA.[2]

Small nucleolar RNA SNORD30
Predicted secondary structure and sequence conservation of SNORD30
Identifiers
SymbolSNORD30
Alt. SymbolsU30
RfamRF00088
Other data
RNA typeGene; snRNA; snoRNA; CD-box
Domain(s)Eukaryota
GO0006396 0005730
SO0000593
PDB structuresPDBe

References

  1. Tycowski KT, Shu MD, Steitz JA (February 1996). "A mammalian gene with introns instead of exons generating stable RNA products". Nature. 379 (6564): 464–6. doi:10.1038/379464a0. PMID 8559254.
  2. Tycowski KT, Smith CM, Shu MD, Steitz JA (December 1996). "A small nucleolar RNA requirement for site-specific ribose methylation of rRNA in Xenopus". Proceedings of the National Academy of Sciences of the United States of America. 93 (25): 14480–5. doi:10.1073/pnas.93.25.14480. PMC 26158. PMID 8962077.
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