Sabinene-hydrate synthase
In enzymology, a sabinene-hydrate synthase (EC 4.2.3.11) is an enzyme that catalyzes the chemical reaction
- geranyl diphosphate + H2O sabinene hydrate + diphosphate
| sabinene-hydrate synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.3.11 | ||||||||
| CAS number | 166800-09-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are geranyl diphosphate and H2O, whereas its two products are sabinene hydrate and diphosphate.
This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is geranyl-diphosphate diphosphate-lyase (cyclizing, sabinene-hydrate-forming). This enzyme is also called sabinene hydrate cyclase. This enzyme participates in monoterpenoid biosynthesis.
References
- Hallahan TW, Croteau R (1988). "Monoterpene biosynthesis: demonstration of a geranyl pyrophosphate:sabinene hydrate cyclase in soluble enzyme preparations from sweet marjoram (Majorana hortensis)". Arch. Biochem. Biophys. 264 (2): 618–31. doi:10.1016/0003-9861(88)90328-1. PMID 3401015.
- Hallahan TW, Croteau R (1989). "Monoterpene biosynthesis: mechanism and stereochemistry of the enzymatic cyclization of geranyl pyrophosphate to (+)-cis- and (+)-trans-sabinene hydrate". Arch. Biochem. Biophys. 269 (1): 313–26. doi:10.1016/0003-9861(89)90113-6. PMID 2916845.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.