Mucin 5AC
Mucin 5AC (Muc5AC) is a protein that in humans is encoded by the MUC5AC gene.[5][6][7]
Clinical relevance
This gene has been linked to mucus hypersecretion in the respiratory tract and is associated to chronic obstructive pulmonary disease (COPD).[8]
gollark: Luckily, I don't have to worry about poor WiFi bandwidth because my *internet* connection is bad too!
gollark: Big text generated by `figlet` on Linux, the *cool* way to write bigly.
gollark: ``` ____ ___ ____ _____ _______ _______ | __ )_ _/ ___| |_ _| ____\ \/ /_ _|| _ \| | | _ | | | _| \ / | | | |_) | | |_| | | | | |___ / \ | | |____/___\____| |_| |_____/_/\_\ |_| ```
gollark: That's because you're eating dinosaurs, not birds.
gollark: Technically, chickens are dinosaurs, not birds.
References
- ENSG00000283158 GRCh38: Ensembl release 89: ENSG00000215182, ENSG00000283158 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000037974 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- Guyonnet Duperat V, Audie JP, Debailleul V, Laine A, Buisine MP, Galiegue-Zouitina S, Pigny P, Degand P, Aubert JP, Porchet N (Feb 1995). "Characterization of the human mucin gene MUC5AC: a consensus cysteine-rich domain for 11p15 mucin genes?". Biochem J. 305 (Pt 1): 211–9. PMC 1136451. PMID 7826332.
- van de Bovenkamp JH, Hau CM, Strous GJ, Buller HA, Dekker J, Einerhand AW (Jun 1998). "Molecular cloning of human gastric mucin MUC5AC reveals conserved cysteine-rich D-domains and a putative leucine zipper motif". Biochem Biophys Res Commun. 245 (3): 853–9. doi:10.1006/bbrc.1998.8535. PMID 9588204.
- "Entrez Gene: MUC5AC mucin 5AC, oligomeric mucus/gel-forming".
- Wang G, Xu Z, Wang R, Al-Hijji M, Salit J, Strulovici-Barel Y, Tilley A, Mezey J, Crystal R (June 2012). "Genes associated with MUC5AC expression in small airway epithelium of human smokers and nonsmokers". BMC Med. Genom. 5 (1): 21. doi:10.1186/1755-8794-5-21. PMC 3443416. PMID 22676183.
External links
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Mucin-5AC
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.