MacVector

MacVector is a commercial sequence analysis application for Apple Macintosh computers running Mac OS X. It is intended to be used by molecular biologists to help analyze, design, research and document their experiments in the laboratory.

MacVector
Developer(s)MacVector, Inc.
Stable release
17.5 / 5 February 2020
Operating systemmacOS
PlatformXcode
TypeBioinformatics
Licensecommercial
Websitemacvector.com

Features

MacVector is a collection of sequence analysis algorithms linked to various sequence editors, including a single sequence editor, a multiple sequence alignment editor and a contig editor. MacVector tries to use a minimum of windows and steps to access all the functionality. Functions include:

  • Sequence alignment (ClustalW, Muscle and T-Coffee) and editing.
  • Subsequence search and open reading frames (ORFs) analysis.
  • Phylogenetic tree construction UPGMA, Neighbour joining with bootstrapping and consensus trees
  • Online Database searching - Search public databases at the NCBI such as Genbank, PubMed, and UniProt.
  • Perform online BLAST searches.
  • Protein analysis.
  • Contig assembly and chromatogram editing
  • Aligning cDNA against genomic templates
  • Creating dot plots of DNA to DNA, Protein to Protein and DNA to protein.
  • Restriction analysis - find and view restriction cut sites. Uses digested fragments to clone genes into vectors. Stores a history of digested fragments allowing multi fragment ligations.
  • PCR Primer design - easy primer design and testing. Also uses primer3
  • Agarose Gel simulation.
  • CRISPR INDEL analysis.

MacVector has a contig assembly plugin called Assembler that uses phred, phrap, Bowtie, SPAdes, Velvet and cross match.

As of version 13.0.1 MacVector uses Sparkle for updating between releases.

History

MacVector was originally developed by IBI in 1994.[1] It was acquired by Kodak, and subsequently Oxford Molecular in 1996.[2][3] Oxford Molecular was merged into Accelrys in 2001.[4] It was acquired by MacVector, Inc on 1 January 2007.[5]

gollark: I need to write a macro for that.
gollark: National security reasons.
gollark: > People with confusing dreams are no longer allowed to reproduceThat would create pressure for less confusing dreams, not realistic ones. Or just lying.
gollark: Do I have to say "chronometer" or something?
gollark: CEASE.

References
  1. "MacVector: an integrated sequence analysis program for the Macintosh". Olson SA. Methods Mol Biol. (1994) 25,195-201.
  2. "DNA Sequencing Software - Special Ad Section". Science. 7 June 1996.
  3. http://findarticles.com/p/articles/mi_hb197/is_/ai_n5566980#%5B%5D
  4. "About Accelrys, including company leadership, recognition, and news". Accelrys.com. 2009-05-04. Retrieved 2012-07-26.
  5. "Accelrys - Additional Products". accelrys.com. Archived from the original on 2008-06-07. Retrieved 2012-07-24.
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