Lymphomatoid papulosis

Lymphomatoid papulosis (LyP) is a rare skin disorder. The overall prevalence rate of lymphomatoid papulosis is estimated at 1.2 to 1.9 cases per 1,000,000 population. This rare condition has only been studied in depth since 1968.[1]

Lymphomatoid papulosis
SpecialtyDermatology 

Presentation

It can appear very similar to anaplastic large cell lymphoma.[2] Type "A" is CD30 positive, while type "B" is CD30 negative.[3]

It has been described as "clinically benign but histologically malignant."[4]

Cause

Diagnosis

Treatment

It may respond to methotrexate or PUVA.[5]

Prognosis

It can evolve into lymphoma.[6]

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See also
  • Cutaneous T-cell lymphoma
  • Parapsoriasis
  • Secondary cutaneous CD30+ large cell lymphoma
  • List of cutaneous conditions

References
  1. Macaulay WL (January 1968). "Lymphomatoid papulosis. A continuing self-healing eruption, clinically benign--histologically malignant". Arch Dermatol. 97 (1): 23–30. doi:10.1001/archderm.97.1.23. PMID 5634442.
  2. El Shabrawi-Caelen L, Kerl H, Cerroni L (April 2004). "Lymphomatoid papulosis: reappraisal of clinicopathologic presentation and classification into subtypes A, B, and C". Arch Dermatol. 140 (4): 441–7. doi:10.1001/archderm.140.4.441. PMID 15096372. Archived from the original on 2011-05-24.
  3. Neal S. Young; Stanton L. Gerson; Katherine A. High (2006). Clinical hematology. Elsevier Health Sciences. pp. 555–. ISBN 978-0-323-01908-8. Retrieved 14 May 2011.
  4. Maria Proytcheva (14 March 2011). Diagnostic Pediatric Hematopathology. Cambridge University Press. pp. 544–. ISBN 978-0-521-88160-9. Retrieved 15 May 2011.
  5. Magro CM, Crowson AN, Morrison C, Merati K, Porcu P, Wright ED (April 2006). "CD8+ lymphomatoid papulosis and its differential diagnosis". Am. J. Clin. Pathol. 125 (4): 490–501. doi:10.1309/NNV4-L5G5-A0KF-1T06. PMID 16627259.
  6. Dalle S, Balme B, Thomas L (2006). "Lymphomatoid papulosis localized to the face". Dermatol. Online J. 12 (3): 9. PMID 16638423.
Classification
External resources
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