Lunamarine

Lunamarine (punarnavine) is a quinolone alkaloid present in Boerhavia diffusa (punarnava).

Lunamarine
Names
IUPAC name
2-(1,3-Benzodioxol-5-yl)-7-methoxy-1-methylquinolin-4-one
Identifiers
3D model (JSmol)
ChemSpider
Properties
C18H15NO14
Molar mass 469.311 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

The compound has shown some in vitro anticancer,[1] antiestrogenic,[2] immunomodulatory,[3] and anti-amoebic activity (particularly against Entamoeba histolytica).[4]

References

  1. Manu K.A.; Kuttan G. (2009). "Punarnavine induces apoptosis in B16F-10 melanoma cells by inhibiting NF-kappaB signaling". Asian Pacific Journal of Cancer Prevention. 10 (6): 1031–1037. PMID 20192578.
  2. Sreeja S.; Sreeja S. (2009). "An in vitro study on antiproliferative and antiestrogenic effects of Boerhaavia diffusa L. extracts". Journal of Ethnopharmacology. 126 (2): 221–225. doi:10.1016/j.jep.2009.08.041. PMID 19723573.
  3. Manu K.A.; Kuttan G. (2009). "Immunomodulatory activities of Punarnavine, an alkaloid from Boerhaavia diffusa". Immunopharmacology and Immunotoxicology. 31 (3): 377–387. doi:10.1080/08923970802702036. PMID 19555203.
  4. Sohni YR.; Kaimal P.; Bhatt RM. (Jan 1995). "The antiamoebic effect of a crude drug formulation of herbal extracts against Entamoeba histolytica in vitro and in vivo". Journal of Ethnopharmacology. 45 (1): 43–52. doi:10.1016/0378-8741(94)01194-5.


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