Isomaltulose synthase
In enzymology, an isomaltulose synthase (EC 5.4.99.11) is an enzyme that catalyzes the chemical reaction
- sucrose 6-O-Alpha-D-Glucopyranosyl-D-Fructofuranose
| isomaltulose synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 5.4.99.11 | ||||||||
| CAS number | 159940-49-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Hence, this enzyme has one substrate, sucrose, and one product, 6-O-Alpha-D-Glucopyranosyl-D-Fructofuranose.
This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring other groups. The systematic name of this enzyme class is sucrose glucosylmutase. Other names in common use include isomaltulose synthetase, sucrose alpha-glucosyltransferase, and trehalulose synthase.
Structural studies
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1M53, 1ZJA, 1ZJB, 2PWD, 2PWE, 2PWF, and 2PWG.
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gollark: Well, the garbage collector does it apparently.
gollark: You can't close files with anything other then their handle methods.
gollark: It's a program which (theoretically...) allows you (on Linux) to mount a computer's filesystem as if it's on your local machine.
gollark: Maybe if you use CCFuse and run the actual git commands outofgame?
References
- Cheetham PS (1984). "The extraction and mechanism of a novel isomaltulose-synthesizing enzyme from Erwinia rhapontici". Biochem. J. 220 (1): 213–20. PMC 1153612. PMID 6743261.
- Cheetham PS, Imber CE, Isherwood J (1982). "The formation of isomaltulose by immobilized Erwinia rhapontici". Nature. 299 (5884): 628–631. doi:10.1038/299628a0.
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