Gamma-curcumene synthase

Gamma-curcumene synthase (EC 4.2.3.94, PatTpsA (gene)) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, gamma-curcumene-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate gamma-curcumene + diphosphate
Gamma-curcumene synthase
Identifiers
EC number4.2.3.94
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme is one of five sesquiterpenoid synthases in Pogostemon cablin (patchouli).

References

  1. Deguerry F, Pastore L, Wu S, Clark A, Chappell J, Schalk M (October 2006). "The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases". Archives of Biochemistry and Biophysics. 454 (2): 123–36. doi:10.1016/j.abb.2006.08.006. PMID 16970904.
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