Galactarate dehydratase
In enzymology, a galactarate dehydratase (EC 4.2.1.42) is an enzyme that catalyzes the chemical reaction
- D-galactarate 5-dehydro-4-deoxy-D-glucarate + H2O
| galactarate dehydratase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.1.42 | ||||||||
| CAS number | 37290-78-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Hence, this enzyme has one substrate, D-galactarate, and two products, 5-dehydro-4-deoxy-D-glucarate and H2O.
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-galactarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming). This enzyme is also called D-galactarate hydro-lyase. This enzyme participates in ascorbate and aldarate metabolism.
References
- Blumenthal HJ; Jepson T (1966). "Galactarate dehydrase". Carbohydrate Metabolism. Methods in Enzymology. 9. pp. 665–669. doi:10.1016/0076-6879(66)09135-3. ISBN 978-0-12-181809-8.
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