Fenticlor

Fenticlor (also spelled fentichlor) is an antibacterial and antifungal agent for topical use. It is an antimicrobial agent. It is also used in veterinary medicine.

Fenticlor
Clinical data
Routes of
administration
topical
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.002.336
Chemical and physical data
FormulaC12H8Cl2O2S
Molar mass287.15 g·mol−1
Melting point174 °C (345 °F)

Synthesis

It is prepared by the AlCl3-catalyzed reaction of 4-chlorophenol with sulfur dichloride.[1] It can also be prepared by chlorination of bis[2-hydroxyphenyl]sulfide.[2][3]

Safety

LD50 (rats, oral) = 3250 mg/kg.[1] It may cause photosensitivity [4]

gollark: It can simulate any Turing machine, except ones which compute exponents (or use more than 92TB of tape).
gollark: C has a weird feature where it's Turing-complete apart from exponents.
gollark: I was just instructed by my superiors in the next universe up to inform you that it is in fact "already too late", whatever that means.
gollark: Maybe I already guessed, as you.
gollark: You should already know it then.

References

  1. Fiege H, Voges HW, Hamamoto T, Umemura S, Iwata T, Miki H, Fujita Y, Buysch HJ, Garbe D, Paulus W (2007). "Phenol Derivatives". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a19_313.
  2. DE 568944, Muth F, "Verfahren zur Darstellung von Bis-(halogen-oxyaryl)-sulfiden", issued 1931, assigned to I. G. Farben
  3. Dunning F, Dunning B, Drake WE (1931). "Preparation and Bacteriological Study of Some Symmetrical Organic Sulfides". Journal of the American Chemical Society. 53 (9): 3466. doi:10.1021/ja01360a035.
  4. Burry JN (June 1974). "Letter: Fenticlor, actinic reticuloid, and antihistamines". British Medical Journal. 2 (5918): 556–7. doi:10.1136/bmj.2.5918.556-c. PMC 1610938. PMID 4152080.
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