Elisabethatriene synthase

Elisabethatriene synthase (EC 4.2.3.41, elisabethatriene cyclase) is an enzyme with systematic name geranylgeranyl-diphosphate diphosphate-lyase (elisabethatriene-forming).[1][2] This enzyme catalyses the following chemical reaction

geranylgeranyl diphosphate elisabethatriene + diphosphate
Elisabethatriene synthase
Identifiers
EC number4.2.3.41
CAS number334022-59-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme requires Mg2+ or less efficiently Mn2+.

References

  1. Kohl AC, Kerr RG (April 2004). "Identification and characterization of the pseudopterosin diterpene cyclase, elisabethatriene synthase, from the marine gorgonian, Pseudopterogorgia elisabethae". Archives of Biochemistry and Biophysics. 424 (1): 97–104. doi:10.1016/j.abb.2004.01.019. PMID 15019841.
  2. Brück TB, Kerr RG (March 2006). "Purification and kinetic properties of elisabethatriene synthase from the coral Pseudopterogorgia elisabethae". Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 143 (3): 269–78. doi:10.1016/j.cbpb.2005.11.016. PMID 16423548.


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