Dihydroxyfumarate decarboxylase
In enzymology, a dihydroxyfumarate decarboxylase (EC 4.1.1.54) is an enzyme that catalyzes the chemical reaction
- dihydroxyfumarate tartronate semialdehyde + CO2
| dihydroxyfumarate decarboxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.1.1.54 | ||||||||
| CAS number | 37289-51-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Hence, this enzyme has one substrate, dihydroxyfumarate, and two products, tartronate semialdehyde and CO2.
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is dihydroxyfumarate carboxy-lyase (tartronate-semialdehyde-forming). This enzyme is also called dihydroxyfumarate carboxy-lyase. This enzyme participates in glyoxylate and dicarboxylate metabolism.
References
- Fukumaga K. "Metabolism of dihydroxyfumarate, hydroxypyruvate, and their related compounds. I. Enzymic formation of xylulose in liver". J. Tokyo. Biochem.: 741–754.
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