Cis-abienol synthase
Cis-abienol synthase (EC 4.2.3.140, Z-abienol synthase, CAS, ABS) is an enzyme with systematic name (13E)-8alpha-hydroxylabd-13-en-15-yl-diphosphate-lyase (cis-abienol forming).[1][2] This enzyme catalyses the following chemical reaction
- (13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate cis-abienol + diphosphate
| Cis-abienol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.3.140 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme is isolated from the plants Abies balsamea (balsam fir) and Nicotiana tabacum (tobacco).
References
- Zerbe P, Chiang A, Yuen M, Hamberger B, Hamberger B, Draper JA, Britton R, Bohlmann J (April 2012). "Bifunctional cis-abienol synthase from Abies balsamea discovered by transcriptome sequencing and its implications for diterpenoid fragrance production". The Journal of Biological Chemistry. 287 (15): 12121–31. doi:10.1074/jbc.m111.317669. PMC 3320957. PMID 22337889.
- Sallaud C, Giacalone C, Töpfer R, Goepfert S, Bakaher N, Rösti S, Tissier A (October 2012). "Characterization of two genes for the biosynthesis of the labdane diterpene Z-abienol in tobacco (Nicotiana tabacum) glandular trichomes". The Plant Journal. 72 (1): 1–17. doi:10.1111/j.1365-313x.2012.05068.x. PMID 22672125.
External links
- Cis-abienol+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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