Cholesterolosis of gallbladder

In surgical pathology, strawberry gallbladder, more formally cholesterolosis of the gallbladder and gallbladder cholesterolosis, is a change in the gallbladder wall due to excess cholesterol.[1]

Cholesterolosis of gallbladder
Micrograph of cholesterolosis of the gallbladder, with an annotated foam cell. H&E stain.
SpecialtyGastroenterology 

The name strawberry gallbladder comes from the typically stippled appearance of the mucosal surface on gross examination, which resembles a strawberry. Cholesterolosis results from abnormal deposits of cholesterol esters in macrophages within the lamina propria (foam cells) and in mucosal epithelium. The gallbladder may be affected in a patchy localized form or in a diffuse form. The diffuse form macroscopically appears as a bright red mucosa with yellow mottling (due to lipid), hence the term strawberry gallbladder. It is not tied to cholelithiasis (gallstones) or cholecystitis (inflammation of the gallbladder).[2]

Additional images
  • Cholesterolosis of the gallbladder (gross image)
  • Micrograph of cholesterolosis of the gallbladder
  • Micrograph of cholesterolosis of the gallbladder
  • Micrograph of cholesterolosis of the gallbladder
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See also

References
  1. Strawberry gallbladder - cancerweb.ncl.ac.uk.
  2. "Cholesterolosis of the Gall Bladder".

Further reading
  • Izzo L, Boschetto A, Brachini G, et al. (2001). "["Strawberry" gallbladder: review of the literature and our experience]". Il Giornale di Chirurgia (in Italian). 22 (1–2): 33–6. PMID 11272434.
Classification
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