Chemical modification

Chemical modification refers to a number of various processes involving the alteration of the chemical constitution or structure of molecules.

History

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Foundations of Chemical Modification

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Chemical Modification in Chemistry

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Chemical modification describes the conversion of macromolecules through a chemical reaction or series of reactions.

Chemically Modified Electrodes

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Chemically modified electrodes are electrodes that have their surfaces chemically converted to change the electrode's properties, such as its physical, chemical, electrochemical, optical, electrical, and transport characteristics. These electrodes are used for advanced purposes in research and investigation.[1]

Chemical modification in biochemistry

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In biochemistry, chemical modification is the technique of anatomically reacting a protein or nucleic acid with a reagent or reagents. Obtaining laboratory information through chemical modification which can be utilized to:

  • identify which parts of a molecule are exposed to a solvent.
  • determine which residues are important for a particular phenotype, e.g., which residues are important for an enzymatic activity;
  • introduce new groups into a macromolecule; and
  • crosslink macromolecules intra- and intermolecularly.

Chemical modification of protein side chains

Chemical modification of nucleic acids
gollark: If you can simulate the plane down to parts-level, which is admittedly probably quite hard (but computers inevitably get faster), you can just randomly generate failure cases.
gollark: One of those, probably.
gollark: Try simulating better.
gollark: I've read the abstracts of *at least* two AI papers on an entirely different topic.
gollark: Not really anything, but at least this sort of fast control task.

References
  1. Durst, R., Baumner, A., Murray, R., Buck, R., & Andrieux, C., "Chemically modified electrodes: Recommended terminology and definitions (PDF)", IUPAC, 1997, pp 1317–1323.


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