Carotenoid 1,2-hydratase

Carotenoid 1,2-hydratase (EC 4.2.1.131, CrtC) is an enzyme with systematic name lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming).[1][2] This enzyme catalyses the following chemical reaction

(1) 1-hydroxy-1,2-dihydrolycopene lycopene + H2O
(2) 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene 1-hydroxy-1,2-dihydrolycopene + H2O
Carotenoid 1,2-hydratase
Identifiers
EC number4.2.1.131
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

In Rubrivivax gelatinosus and Thiocapsa roseopersicina both products are formed.

References

  1. Steiger S, Mazet A, Sandmann G (June 2003). "Heterologous expression, purification, and enzymatic characterization of the acyclic carotenoid 1,2-hydratase from Rubrivivax gelatinosus". Archives of Biochemistry and Biophysics. 414 (1): 51–8. doi:10.1016/s0003-9861(03)00099-7. PMID 12745254.
  2. Hiseni A, Arends IW, Otten LG (August 2011). "Biochemical characterization of the carotenoid 1,2-hydratases (CrtC) from Rubrivivax gelatinosus and Thiocapsa roseopersicina". Applied Microbiology and Biotechnology. 91 (4): 1029–36. doi:10.1007/s00253-011-3324-1. PMC 3145076. PMID 21590288.
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