CC-1088
CC-1088 is a thalidomide analogue inhibitor of phosphodiesterase 4 that was being developed up to 2005 by Celgene Corp., for treating of inflammatory diseases and myelodysplastic syndromes.[1] Apremilast (CC-10004) was found to be a preferable.[2]
Skeletal formula
See also
- Apremilast
- Development of analogs of thalidomide
References
- K. Dredge (May 2005). "CC-1088 Celgene". Current Opinion in Investigational Drugs. 6 (5): 513–7. PMID 15912966.
- Molostvov G, Morris A, Rose P, Basu S, Muller G (February 2004). "The effects of selective cytokine inhibitory drugs (CC-10004 and CC-1088) on VEGF and IL-6 expression and apoptosis in myeloma and endothelial cell co-cultures". British Journal of Haematology. 124 (3): 366–75. doi:10.1046/j.1365-2141.2003.04777.x. PMID 14717786.
External links
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