Beta-phellandrene synthase (neryl-diphosphate-cyclizing)

Beta-phellandrene synthase (neryl-diphosphate-cyclizing) (EC 4.2.3.51, phellandrene synthase 1, PHS1, monoterpene synthase PHS1) is an enzyme with systematic name neryl-diphosphate diphosphate-lyase (cyclizing; beta-phellandrene-forming).[1] This enzyme catalyses the following chemical reaction

neryl diphosphate beta-phellandrene + diphosphate
Beta-phellandrene synthase (neryl-diphosphate-cyclizing)
Identifiers
EC number4.2.3.51
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

The enzyme from Solanum lycopersicum has very poor affinity with geranyl diphosphate.

References

  1. Schilmiller AL, Schauvinhold I, Larson M, Xu R, Charbonneau AL, Schmidt A, Wilkerson C, Last RL, Pichersky E (June 2009). "Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate". Proceedings of the National Academy of Sciences of the United States of America. 106 (26): 10865–70. doi:10.1073/pnas.0904113106. PMC 2705607. PMID 19487664.
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