Arsenate reductase (donor)

Arsenate reductase (donor) (EC 1.20.99.1) is an enzyme that catalyzes the chemical reaction

arsenite + acceptor arsenate + reduced acceptor
arsenate reductase (donor)
Identifiers
EC number1.20.99.1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are arsenite and an acceptor, whereas its two products are arsenate and a reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on phosphorus or arsenic in donor with other acceptors. The systematic name of this enzyme class is arsenate:acceptor oxidoreductase. This enzyme is also called arsenate:(acceptor) oxidoreductase.

References

    • Krafft T, Macy JM (1998). "Purification and characterization of the respiratory arsenate reductase of Chrysiogenes arsenatis". Eur. J. Biochem. 255 (3): 647–53. doi:10.1046/j.1432-1327.1998.2550647.x. PMID 9738904.
    • Radabaugh TR, Aposhian HV (2000). "Enzymatic reduction of arsenic compounds in mammalian systems: reduction of arsenate to arsenite by human liver arsenate reductase". Chem. Res. Toxicol. 13 (1): 26–30. doi:10.1021/tx990115k. PMID 10649963.
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