Arabidiol synthase

Arabidiol synthase (EC 4.2.1.124, PEN1 (gene), (S)-squalene-2,3-epoxide hydro-lyase (arabidiol forming)) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene hydro-lyase (arabidiol forming).[1] This enzyme catalyses the following chemical reaction

arabidiol (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
Arabidiol synthase
Identifiers
EC number4.2.1.124
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

The reaction occurs in the reverse direction.

References

  1. Xiang T, Shibuya M, Katsube Y, Tsutsumi T, Otsuka M, Zhang H, Masuda K, Ebizuka Y (June 2006). "A new triterpene synthase from Arabidopsis thaliana produces a tricyclic triterpene with two hydroxyl groups". Organic Letters. 8 (13): 2835–8. doi:10.1021/ol060973p. PMID 16774269.
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