Antimigraine drug

Antimigraine drugs are medications intended to reduce the effects or intensity of migraine headache. They include drugs for the treatment of acute migraine symptoms as well as drugs for the prevention of migraine attacks.[1]

Antimigraine drug
Drug class
Zolmitriptan, a common antimigraine medication
Class identifiers
UseMigraine therapy and prevention
ATC codeN02C
Clinical data
Drugs.comDrug Classes
In Wikidata

Examples

Treatment of acute symptoms

Migraine can often be treated with unspecific analgesics such as nonsteroidal anti-inflammatory drugs (NSAIDs) or paracetamol, with or without metoclopramide. Examples of specific antimigraine drugs include triptans[2] such as zolmitriptan[3] and ergot alkaloids such as methysergide.

Prevention

First-line drugs for the prevention of migraine attacks include the beta blockers propranolol, metoprolol and bisoprolol, the antiepileptics valproic acid and topiramate, as well as flunarizine. Less well evidenced is the use of amitriptyline, venlafaxine, Petasites albus extract, riboflavin (vitamin B2), magnesium, coenzyme Q10, gabapentin, acetylsalicylic acid, and naproxen.[1]

gollark: Yes, the IO monad is better than laziness insanity, which is why Haskell switched to moads.
gollark: You can only return once, but the return can be a string which isn't fully evaluated until later.
gollark: No, in the old lazy haskell.
gollark: Strings are actually linked lists of characters by default due to extremely large brain sizes.
gollark: `main = putStrLn "Greetings, foolish mortal. Bow before the power of mÖnad."`

References

  1. Mutschler, Ernst (2013). Arzneimittelwirkungen (in German) (10 ed.). Stuttgart: Wissenschaftliche Verlagsgesellschaft. pp. 232–5. ISBN 978-3-8047-2898-1.
  2. pharmamotion.com > Serotonin (5-HT): receptors, agonists and antagonists Archived 2009-09-15 at the Wayback Machine By Flavio Guzmán, M.D. on 9/08/09
  3. Morikawa T, Matsuzawa Y, Makita K, Katayama Y (2006). "Antimigraine drug, zolmitriptan, inhibits high-voltage activated calcium currents in a population of acutely dissociated rat trigeminal sensory neurons". Molecular Pain. 2 (1): 10. doi:10.1186/1744-8069-2-10. PMC 1434723. PMID 16549032.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.