Alphanodavirus

Alphanodavirus is a genus of viruses, in the family Nodaviridae.[3] Insects, mammals, and fishes serve as natural hosts. There are currently five species in this genus including the type species Nodamura virus. Diseases associated with this genus include: NoV: paralysis in infected wax moth larvae. It can also provoke paralysis and death to suckling mice and suckling hamsters.[4][5]

Alphanodavirus
Structure of Nodamura virus[1]
Virus classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Kitrinoviricota
Class: Magsaviricetes
Order: Nodamuvirales
Family: Nodaviridae
Genus: Alphanodavirus
Type species
Nodamura virus
Species[2]

Structure

Viruses in the genus Alphanodavirus are non-enveloped, with icosahedral geometries, and T=3 symmetry. The diameter is around 30 nm. Genomes are linear and segmented, bipartite, around 21.4kb in length.[4][5]

GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
AlphanodavirusIcosahedralT=3Non-envelopedLinearSegmented

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by penetration into the host cell. Replication follows the positive stranded RNA virus replication model. Positive stranded rna virus transcription, using the internal initiation model of subgenomic RNA transcription is the method of transcription. Insects, mammals, and fishes serve as the natural host.[4][5]

GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
AlphanodavirusInsects, mammals, fishesNonePenetrationLysisCytoplasmCytoplasmUnknown
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References
  1. "1NOV." RCSB PDB. N.p., n.d. Web. 10 Dec. 2015.
  2. "Virus Taxonomy: 2018b Release". International Committee on Taxonomy of Viruses (ICTV). March 2019. Retrieved 20 May 2019.
  3. Sahul Hameed, AS; Ninawe, AS; Nakai, T; Chi, SC; Johnson, KL; ICTV Report, Consortium (January 2019). "ICTV Virus Taxonomy Profile: Nodaviridae". The Journal of General Virology. 100 (1): 3–4. doi:10.1099/jgv.0.001170. PMID 30431412.
  4. "ICTV Report Nodaviridae".
  5. "Viral Zone". ExPASy. Retrieved 12 June 2015.
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