Alpha-gurjunene synthase
Alpha-gurjunene synthase (EC 4.2.3.72) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((-)-alpha-gurjunene-forming).[1] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate (-)-alpha-gurjunene + diphosphate
| Alpha-gurjunene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.3.72 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Initial cyclization probably gives biyclogermacrene in an enzyme bound form.
References
- Schmidt CO, Bouwmeester HJ, Bülow N, König WA (April 1999). "Isolation, characterization, and mechanistic studies of (-)-alpha-gurjunene synthase from Solidago canadensis". Archives of Biochemistry and Biophysics. 364 (2): 167–77. doi:10.1006/abbi.1999.1122. PMID 10190971.
External links
- Alpha-gurjunene+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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