4-hydroxyphenylpyruvate decarboxylase
In enzymology, a 4-hydroxyphenylpyruvate decarboxylase (EC 4.1.1.80) is an enzyme that catalyzes the chemical reaction
- 4-hydroxyphenylpyruvate 4-hydroxyphenylacetaldehyde + CO2
| 4-hydroxyphenylpyruvate decarboxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.1.1.80 | ||||||||
| CAS number | 109300-96-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Hence, this enzyme has one substrate, 4-hydroxyphenylpyruvate, and two products, 4-hydroxyphenylacetaldehyde and CO2.
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 4-hydroxyphenylpyruvate carboxy-lyase (4-hydroxyphenylacetaldehyde-forming). This enzyme is also called 4-hydroxyphenylpyruvate carboxy-lyase.
References
- Rueffer M, Zenk MH (1987). "Distant precursors of benzylisoquinoline alkaloids and their enzymatic formation". Z. Naturforsch. C: Biosci. 42: 319–332.
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