4,5-dihydroxyphthalate decarboxylase
In enzymology, a 4,5-dihydroxyphthalate decarboxylase (EC 4.1.1.55) is an enzyme that catalyzes the chemical reaction
- 4,5-dihydroxyphthalate 3,4-dihydroxybenzoate + CO2
| 4,5-dihydroxyphthalate decarboxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.1.1.55 | ||||||||
| CAS number | 37290-48-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Hence, this enzyme has one substrate, 4,5-dihydroxyphthalate, and two products, 3,4-dihydroxybenzoate and CO2.
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 4,5-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming). This enzyme is also called 4,5-dihydroxyphthalate carboxy-lyase. This enzyme participates in 2,4-dichlorobenzoate degradation.
References
- Ribbons DW, Evans WC (1966). "Oxidative metabolism of phthalic acid by soil pseudomonads". Biochem. J. 76: 310–318.
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