3-dehydroshikimate dehydratase

3-dehydroshikimate dehydratase (EC 4.2.1.118) is an enzyme with systematic name 3-dehydroshikimate hydro-lyase.[1][2] This enzyme catalyses the following chemical reaction

3-dehydro-shikimate protocatechuate + H2O
3-dehydroshikimate dehydratase
Identifiers
EC number4.2.1.118
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme catalyses an early step in the biosynthesis of petrobactin.

References

  1. Fox DT, Hotta K, Kim CY, Koppisch AT (November 2008). "The missing link in petrobactin biosynthesis: asbF encodes a (-)-3-dehydroshikimate dehydratase". Biochemistry. 47 (47): 12251–3. doi:10.1021/bi801876q. PMID 18975921.
  2. Pfleger BF, Kim Y, Nusca TD, Maltseva N, Lee JY, Rath CM, Scaglione JB, Janes BK, Anderson EC, Bergman NH, Hanna PC, Joachimiak A, Sherman DH (November 2008). "Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis". Proceedings of the National Academy of Sciences of the United States of America. 105 (44): 17133–8. doi:10.1073/pnas.0808118105. PMC 2579390. PMID 18955706.
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