(-)-gamma-cadinene synthase ((2Z,6E)-farnesyl diphosphate cyclizing)

(-)-gamma-cadinene synthase ((2Z,6E)-farnesyl diphosphate cyclizing) (EC 4.2.3.62, (-)-gamma-cadinene cyclase) is an enzyme with the systematic name (2Z,6E)-farnesyl-diphosphate diphosphate-lyase ((-)-gamma-cadinene-forming).[1] This enzyme catalyses the following chemical reaction:

(2Z,6E)-farnesyl diphosphate (-)-gamma-cadinene + [diphosphate]
(-)-gamma-cadinene synthase ((2Z,6E)-farnesyl diphosphate cyclizing)
Identifiers
EC number4.2.3.62
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme is isolated from the liverwort Heteroscyphus planus.

References

  1. Nabeta K, Fujita M, Komuro K, Katayama K, Takasawa T (1997). "In vitro biosynthesis of cadinanes by cell-free extracts of cultured cells of Heteroscyphus planus". J. Chem. Soc., Perkin Trans. 1: 2065–2070.
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