(+)-delta-selinene synthase
(+)-delta-selinene synthase (EC 4.2.3.76) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((+)-delta-selinene-forming).[1][2] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate (+)-delta-selinene + diphosphate
| (+)-delta-selinene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.3.76 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Initial cyclization gives germacrene C in an enzyme bound form.
References
- Steele CL, Crock J, Bohlmann J, Croteau R (January 1998). "Sesquiterpene synthases from grand fir (Abies grandis). Comparison of constitutive and wound-induced activities, and cDNA isolation, characterization, and bacterial expression of delta-selinene synthase and gamma-humulene synthase". The Journal of Biological Chemistry. 273 (4): 2078–89. doi:10.1074/jbc.273.4.2078. PMID 9442047.
- Little DB, Croteau RB (June 2002). "Alteration of product formation by directed mutagenesis and truncation of the multiple-product sesquiterpene synthases delta-selinene synthase and gamma-humulene synthase". Archives of Biochemistry and Biophysics. 402 (1): 120–35. doi:10.1016/S0003-9861(02)00068-1. PMID 12051690.
External links
- (+)-delta-selinene+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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