Ro 3-0412

Ro 3-0412 is an acetylcholinesterase inhibitor. It is the organophosphate analog of neostigmine.[1]

Ro 3-0412
Names
IUPAC name
3-[(Dimethoxyphosphoryl)oxy]-N,N,N-trimethylanilinium methyl sulfate
Other names
Dimethylphosphostigmine
Identifiers
3D model (JSmol)
ChemSpider
Properties
C12H22NO8PS
Molar mass 371.34 g·mol−1
Hazards
Lethal dose or concentration (LD, LC):
0.57 mg/kg (mice, intravenous)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

See also

References

  1. BURGEN, AS; HOBBIGER, F (December 1951). "The inhibition of cholinesterases by alkyl-phosphates and alkylphenolphosphates". British Journal of Pharmacology and Chemotherapy. 6 (4): 593–605. doi:10.1111/j.1476-5381.1951.tb00670.x. PMC 1509150. PMID 14904884.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.