Typical pulmonary carcinoid tumour

Typical pulmonary carcinoid tumour is a subtype of pulmonary carcinoid tumour. It is an uncommon low-grade malignant lung mass that is most often in the central airways of the lung.[1]

Typical pulmonary carcinoid tumour
Other namesTypical lung carcinoid tumour, lung carcinoid, typical lung carcinoid
Micrograph of a typical pulmonary carcinoid tumour.
SpecialtyOncology

Signs and symptoms

Lung carcinoids typically present with a cough or hemoptysis.[2] Findings may closely mimic malignant tumours of the lung, i.e. lung cancer.

Diagnosis
CT-guided biopsy of peripheral typical carcinoid tumor

The definitive diagnosis is rendered by a microscopic examination, after excision. Typical carcinoids have cells with stippled chromatin and a moderate quantity of cytoplasm. They typically have few mitoses and lack necrosis. By definition, they are greater than 4 mm in largest dimension; smaller lesions are referred to as pulmonary carcinoid tumourlets.

The differential diagnosis of typical pulmonary carcinoid tumour includes: atypical pulmonary carcinoid tumour, pulmonary carcinoid tumourlet and lung adenocarcinoma.

  • Very high magnification
  • With prominent rosettes

Treatment

Typical carcinoids are usually treated with surgical excision.

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See also

References
  1. Meisinger, QC.; Klein, JS.; Butnor, KJ.; Gentchos, G.; Leavitt, BJ. (Nov 2011). "CT features of peripheral pulmonary carcinoid tumors". AJR Am J Roentgenol. 197 (5): 1073–80. doi:10.2214/AJR.10.5954. PMID 22021498.
  2. Gungor, S.; Damadoglu, E.; Aybatli, A.; Yilmaz, A.; Kir, A.; Akkaya, E. (Jul 2006). "Typical pulmonary carcinoid tumors: presentation and outcome of 24 cases". Med Sci Monit. 12 (7): CR315–8. PMID 16810137.
Classification
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