Tripamide
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Routes of administration | Oral |
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Formula | C16H20ClN3O3S |
Molar mass | 369.86 g·mol−1 |
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Tripamide (INN) is a diuretic.
Synthesis
![](../I/m/Tripamide_synthesis.svg.png)
Tripamide synthesis:[1]
Preparation starts by exhaustive reduction of the Diels-Alder adduct from cyclopentadiene and maleimide (1). Nitrosation of the product (2), followed by reduction of the nitroso group of 3, gives the corresponding hydrazine (4). Acylation with acid chloride 5 gives tripamide (6).
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