Tilorone

Tilorone (trade names Amixin, Lavomax and others) is the first recognized synthetic, small molecular weight compound that is an orally active interferon inducer.[2] It is used as an antiviral drug. It is effective against Ebola virus in mice.[3]

Tilorone
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
By mouth (tablets)
ATC code
Pharmacokinetic data
Bioavailability60%
Protein binding~80%
MetabolismNil
Elimination half-life48 hours
ExcretionFeces (70%), urine (9%)[1]
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC25H34N2O3
Molar mass410.558 g·mol−1
3D model (JSmol)
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Pharmacology

Tilorone activates the production of interferon.[2]

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References

  1. "Registry of Medicinal Products (RLS). Tilorone: Prescribing Information" (in Russian). Retrieved 2 October 2016.
  2. Stringfellow D, Glasgow L (1972). "Tilorone hydrochloride: an oral interferon-inducing agent". Antimicrob Agents Chemother. 2 (2): 73–8. doi:10.1128/aac.2.2.73. PMC 444270. PMID 4670490.
  3. https://pubmed.ncbi.nlm.nih.gov/29133569/
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