Tilorone
Tilorone (trade names Amixin, Lavomax and others) is the first recognized synthetic, small molecular weight compound that is an orally active interferon inducer.[2] It is used as an antiviral drug. It is effective against Ebola virus in mice.[3]
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| AHFS/Drugs.com | International Drug Names |
| Routes of administration | By mouth (tablets) |
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| Pharmacokinetic data | |
| Bioavailability | 60% |
| Protein binding | ~80% |
| Metabolism | Nil |
| Elimination half-life | 48 hours |
| Excretion | Feces (70%), urine (9%)[1] |
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| Chemical and physical data | |
| Formula | C25H34N2O3 |
| Molar mass | 410.558 g·mol−1 |
| 3D model (JSmol) | |
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Pharmacology
Tilorone activates the production of interferon.[2]
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References
- "Registry of Medicinal Products (RLS). Tilorone: Prescribing Information" (in Russian). Retrieved 2 October 2016.
- Stringfellow D, Glasgow L (1972). "Tilorone hydrochloride: an oral interferon-inducing agent". Antimicrob Agents Chemother. 2 (2): 73–8. doi:10.1128/aac.2.2.73. PMC 444270. PMID 4670490.
- https://pubmed.ncbi.nlm.nih.gov/29133569/
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