Thecoma
Thecomas or theca cell tumors are benign ovarian neoplasms composed only of theca cells. Histogenetically they are classified as sex cord-stromal tumours.
| Thecoma | |
|---|---|
 | |
| High magnification micrograph of a thecoma. H&E stain. | |
| Specialty | Oncology  |
They are typically estrogen-producing and they occur in older women (mean age 59; 84% after menopause). (They can, however, appear before menopause.[1])
60% of patients present with abnormal uterine bleeding, and 20% have endometrial carcinoma.
Pathologic features
Low magnification micrograph of a thecoma showing compression of the ovarian cortex (right of image). H&E stain.
Grossly, the tumour is solid and yellow.
Grossly and microscopically, it consists of the ovarian cortex.
Microscopically, the tumour cells have abundant lipid-filled cytoplasm.
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References
- Okada I, Nakagawa S, Takemura Y, et al. (October 2004). "Ovarian thecoma associated in the first trimester of pregnancy". J. Obstet. Gynaecol. Res. 30 (5): 368–71. doi:10.1111/j.1447-0756.2004.00212.x. PMID 15327450.
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