TIMM17A

Mitochondrial import inner membrane translocase subunit Tim17-A is an enzyme that in humans is encoded by the TIMM17A gene.[5][6][7]

TIMM17A
Identifiers
Aliases	TIMM17A, TIM17, TIM17A, translocase of inner mitochondrial membrane 17 homolog A (yeast), translocase of inner mitochondrial membrane 17A
External IDs	OMIM: 605057 MGI: 1343131 HomoloGene: 115910 GeneCards: TIMM17A
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q32.1 Start 201,955,503 bp[1] End 201,970,664 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 E4 Start 135,295,213 bp[2] End 135,313,778 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • P-P-bond-hydrolysis-driven protein transmembrane transporter activity • protein transmembrane transporter activity Cellular component • nucleoplasm • integral component of mitochondrial inner membrane • mitochondrial inner membrane • integral component of membrane • TIM23 mitochondrial import inner membrane translocase complex • mitochondrion • membrane Biological process • protein targeting to mitochondrion • protein import into mitochondrial matrix • protein transport • intracellular protein transport • positive regulation of protein processing Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10440	21854
Ensembl	ENSG00000134375	ENSMUSG00000062580
UniProt	Q99595	Q9Z0V8
RefSeq (mRNA)	NM_006335	NM_011590
RefSeq (protein)	NP_006326	NP_035720 NP_001347786 NP_001347787
Location (UCSC)	Chr 1: 201.96 – 201.97 Mb	Chr 1: 135.3 – 135.31 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• Mitochondria Inner Membrane Translocase
• TIMM22
• TIMM23
• TIMM44

References

1. GRCh38: Ensembl release 89: ENSG00000134375 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000062580 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Bomer U, Rassow J, Zufall N, Pfanner N, Meijer M, Maarse AC (Dec 1996). "The preprotein translocase of the inner mitochondrial membrane: evolutionary conservation of targeting and assembly of Tim17". J Mol Biol. 262 (4): 389–395. doi:10.1006/jmbi.1996.0522. PMID 8893850.
6. Bauer MF, Gempel K, Reichert AS, Rappold GA, Lichtner P, Gerbitz KD, Neupert W, Brunner M, Hofmann S (Jul 1999). "Genetic and structural characterization of the human mitochondrial inner membrane translocase". J Mol Biol. 289 (1): 69–82. doi:10.1006/jmbi.1999.2751. PMID 10339406.
7. "Entrez Gene: TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)".

Further reading

• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–1178. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Piesse C, Tymms M, Garrafa E, et al. (2002). "Human aminopeptidase B (rnpep) on chromosome 1q32.2: complementary DNA, genomic structure and expression". Gene. 292 (1–2): 129–140. doi:10.1016/S0378-1119(02)00650-9. PMID 12119107.
• Moro F, Sirrenberg C, Schneider HC, et al. (1999). "The TIM17.23 preprotein translocase of mitochondria: composition and function in protein transport into the matrix". EMBO J. 18 (13): 3667–3675. doi:10.1093/emboj/18.13.3667. PMC 1171444. PMID 10393182.